Description
Selank is a synthetic heptapeptide analogue of tufts in with demonstrated anxiolytic and anti-asthenic (energy-boosting) properties in human clinical trials. In Russian studies, intranasal Selank produced anxiolytic effects comparable to benzodiazepines without sedation or dependence potential. This educational protocol presents a once‑daily subcutaneous approach using practical dilution for accurate insulin‑syringe measurements.
- Reconstitute: Add 3.0 mL bacteriostatic water (max vial capacity) → ~3.33 mg/mL concentration.
- Typical daily range: 300–500 mcg once daily subcutaneously (gradual titration).
- Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33.3 mcg on a U‑100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.
Standard / Gradual Approach (3 mL = ~3.33 mg/mL)
| Week | Daily Dose (mcg) | Units (per injection) (mL) |
|---|---|---|
| Weeks 1–2 | 300 mcg (0.3 mg) | 9 units (0.09 mL) |
| Weeks 3–4 | 500 mcg (0.5 mg) | 15 units (0.15 mL) |
Frequency: Inject once daily subcutaneously. A common cycling pattern is 4 weeks on, 4 weeks off to prevent tachyphylaxis, though continuous daily use has been studied in clinical trials for up to 14 days with good tolerability. Some practitioners recommend administering 5 days per week with 2-day breaks.
For ≤10‑unit (≤0.10 mL) administrations, consider 30‑ or 50‑unit insulin syringes for improved readability.
Reconstitution Steps
- Draw 3.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake vigorously as peptides are delicate).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
